Diabetes

Diabetes

With the social development and improvement of people's living standard, diabetes has become a global disease, is now a serious third after cardiovascular disease and cancer. Diabetes is caused by a lack of insulin secretion or insulin resistance caused by a group of metabolic diseases characterized by chronic hyperglycemia fat carbohydrate-related, and protein metabolism disorders, chronic high blood sugar can lead to dysfunction or failure of the various tissues and organs, especially the eyes, kidneys, nerves and cause damage to blood vessels. Diabetes is divided into type 1 diabetes, type 2 diabetes, gestational diabetes, and other specific types of diabetes.
Mechanisms of stem cell therapy for diabetes

Stem cells are a class of pluripotent cells with the ability to replicate themselves, after the damaged human organs, active stem cells can migrate to damaged organs and differentiate into cells that play a role in repair and regeneration of tissues and organs, the medical profession is called "cell wildcard ". Stem cell transplantation for the treatment of diabetes, based on the unique biological characteristics of stem cells, the ability of strong self-renewal and differentiation potential, so the best seed islet β cells (insulin secretion by pancreatic β cells), increasing the number of pancreatic β cell function to prevent decline pancreatic β cells, as much as possible to save and restore the function of the pancreas.
How stem cells change the function of the pancreas?

Experts Modern Hospital Guangzhou (Stem Cell Research & Treatment Center) said, showed that the stem cells in the treatment of diabetes is not a substitute for simple cells, but through five steps to change the function of the pancreas?

The first step: activate the patient's own islet cells. Stem cell after the intervention, in a very short time a large number of islet cells was activated, its function is restored.

Step 2: Fix the β cell island. Insulin-secreting pancreatic β cells in vivo primary cells. Stem cells have the function of secreting insulin for repair through direct β-cells, and to stimulate the regeneration of pancreatic β cells.

Step 3: stem cells improve insulin secretion cells of the human body other. In the human body, in addition to β-cells that secrete insulin, as well as in other organs and tissues inside the body there are some cells that can secrete insulin. Repair and regeneration of cells by stem cell can increase the secretion of insulin in the body, which may play a role in lowering blood sugar.

Step 4: stem cells play a role in insulin resistance. Improve islet receptor and bind insulin, and reduce the role of insulin resistance.

Step 5: increase the body's own insulin secretion rate. Stem cells can grow pembelahannya in one cycle, the new cells will be increased gradually, to replace the islet cells which aging occurs, at the same time to open a new cycle of metabolism, comprehensive care for diabetes.
Stem cell transplant process:

After collecting colony stimulating factor mobilization of bone marrow stem cell separation → → developed and expanded stem cells directed intervention → pancreas transplantation.
Stem cells in the treatment of diabetes

Transplantation methods commonly used in the treatment of diabetes: transplantation of autologous bone marrow stem cells, blood stem cell transplantation, transplantation of human embryonic stem cells, transplantation of umbilical cord blood stem cells, umbilical cord stem cell transplant mesenchymal

1. Transplantation of autologous bone marrow stem cells: bone marrow of patients with diabetes taking itself, in vitro after the induction drugs, bone marrow stem cells are targeted and directed, so as to differentiate into insulin-producing cells, then the number is increasing, and then injected into the patient to treat diabetes .

2. Blood stem cell transplantation: is the use of blood component separation technology, stem cells of bone marrow is concentrated together in the patient himself, spread in vitro with the help of medicine, stem cell DNA repaired, modified, strengthened, renewed and transformed, and make gene reorganization in insulin-secreting cells, and then by the threat of flu virus carrier input to the appropriate organs of the body of the patient.

3. Transplantation of human embryonic stem cells: embryonic stem cells are isolated in the embryo sac, and the orientation induced to differentiate into cells that can produce insulin and can then be issued, and then transferred to the affected part, will be able to repair the damaged islet tissue, so it can cure diabetes. Embryonic stem cell transplantation has an advantage with low immunogenicity, lower rejection response to light and so on.

4. Transplantation of umbilical cord blood stem cells: umbilical cord blood stem cells have the ability to regenerate, regenerative ability is 10 to 20 times the capacity of bone marrow. Cord blood taken can be developed and targeted, which differentiate into various tissue cells to treat diseases such as diabetes.

5. Transplantation of umbilical cord mesenchymal stem cells: umbilical cord conventional care after the baby is born, collecting umbilical cord, the separation of fresh stem cells, cultivated in the laboratory, above a certain level is inserted in a patient.

What are the advantages of stem cells to treat diabetes?

The emergence of high-tech stem cell to break through the barriers of traditional medicine. Most diseases rooted in cellular damage, stem cell differentiation through specific cells to replace damaged cells in the body, so as to achieve the purpose of reconstruction. What are the benefits of stem cell therapy for diabetes?

1, stem cell therapy for diabetes has a very significant effect. After intravenous injection of stem cells or the intervention into the patient's body to repair damaged cells in the body, stem cells have the ability of self-replication and differentiation, in order to achieve the reconstruction goals bodily functions.

2, stem cell therapy is a form of cell biological therapy, no significant effect on the patient's body. So far, stem cells in the treatment does not cause significant side effects or adverse reactions.

3, the prevalence of stem cells in the blood, bone marrow or peripheral blood human placenta, has the advantage of being easy to obtain, because the stem cells are taken from the body, giving back to the body, so there is no rejection.
Stem cells bring hope for diabetics

Stem cell therapy is a form of cell biology, is an advanced medical technology to break through the barriers of traditional treatment brings hope for diabetes treatment.

With stem cells from the patient's body, which can make normal islet cells, a new generation of islet cell insulin secretion can achieve, without the need for drugs and insulin therapy, to help patients get rid of dependence on insulin and medications. .

Compared with traditional medicine, stem cell treatment highlights the advantages of biotechnology disease.